Replacing Eye Test Dispersion Stability Analysis with the Turbiscan
Colloids and dispersions are inherently unstable systems which can be considered as kinetically stable if the destabilization is enough small compared with the expected lifespan. The analysis of the dispersion instability is of prime importance.
Rudimentary techniques, such as the eye test, are currently being used by a large percentage of labs to determine long term stability of these systems and can be easily affected by user bias and error. The 20 micron optical resolution of the Turbiscan not only increases the accuracy of data acquisition but the detectors are able to see even the slightest changes in stability, resulting in far quicker stability experiments, with up to 200x speed to results.
More advanced techniques that measure particle size and zeta potential are useful in studying the behavior of colloidal systems and dispersion, but the analyses typically require the sample be diluted from its natural state, reducing the scope and accuracy of these techniques in real life conditions. Furthermore, these techniques give information on the interaction between the components of a dispersion, and while that information is extremely critical in formulating a dispersion, detecting and understanding the destabilization mechanisms of a concentrated dispersion over time is of prime importance.
The TURBISCAN was designed to replace the outdated eye test and work in conjunction with particle size and zeta potential analyses to provide a complete understanding of immensely complicated systems. By understanding the destabilization mechanisms (particle migration, particle size variation, etc.) of colloids and dispersions in much greater detail than previous techniques, and combining that with the information obtained from zeta potential and particle size techniques, you have control and insight of every step of the formulation process and ultimately control over the quality of the final product.